Mesuron Inc.MagnetoCardioGraphy ( MCG )

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Mesuron Inc.  is Taking the Art of  Bio-Magnetic Measurements in the Magnetically Unshielded Environment to the Next Revolutionary Level!

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Mesuron's "Avalon-H90" MagnetoCardioGraph (MCG) is the

Ultimate Solution for Emergency Departments (ED) managing Acute Chest Pain Patients

Delivering Ventricle Repolarization Dynamics Analytics (VRDA) results during 3-5 minutes since patient admitted to ED

MagnetoCardioGraphy (MCG)

 

 

Mesuron Inc. is a US commercial company specializing in the development and fabrication of SQUID-based magnetometers for various applications, including MagnetoCardioGraphy (MCG), which is our main interest and the center of our attention. Superconducting Quantum Interference Devices (SQUIDs) known since early 1960-s are the most sensitive sensors of magnetic field. They are capable of measuring extremely weak magnetic signals from a beating heart, clearly distinguishing between healthy and diseased (ischemic) hearts. We have more than 30 years of extensive experience in developing such equipment, but only lately we have achieved a breakthrough in constructing magneto cardiographer that can reliably operate in any open, magnetically non-shielded environment, such as a typical hospitalís emergency room (ER), or intensive care unit (ICU). Before this breakthrough, diagnostic measurements in busy, magnetically noisy environments were either impossible or at least defective. Now, with Mesuronís equipment, they became reliable and accurate. Measurements can be reliably made in close proximity to hospital elevators, all kinds of medical apparatus, moving metal beds, working printers, computers, etc. Needless to say, the magnetic environment in a typical private cardiology office is even more conducive to a smooth operation of our system. 

State of the art sensors, readout electronics and sophisticated software in our latest MCG system "Avalon-H90" makes a single (60-90 seconds), totally non-invasive measurement of time-dependent special distribution of the magnetic field over a patientís torso (patient at rest on a bed), and from that single measurement it delivers valuable diagnostic result in 3-5 minutes -- the result that can be immediately interpreted by a doctor or by a technician.  This is done without any contact with the patient's body, without any kind of induced radiation, and without any injected pharmaceuticals. It is truly non-invasive. This became possible upon development of our proprietary, unique environmental magnetic interference (noise) reduction technology, said noise reduction built into the Mesuron magneto cardiograph, both in hardware and in software.  

Currently  Mesuron Inc. is making MCG systems for the R&D purposes. By customer request, we can certify such a system for safety with CE mark through UL testing and safety evaluation. Mesuron also has plans to have an FDA 510K (safety) approval for the MCG system "Avalon-H90". 

"Mesuron MCG system such asďAvalon-90Ē can deliver heart Ventricle Repolarization Dynamics Analysis (VRDA) during 3-5 minutes; that includes taking the cardiac data during only 90 seconds or less. The result of the VRDA is similar to what SPECT does. The reason for this similarity is clear: hypoxia of some region of the heart muscles manifests itself in both diagnostics. SPECT detects the regions of the heart with hypoxia (reduced delivery of blood supply) using the radioactive chemical containing Thallium that acts similar to oxygen. Scanning the heart, SPECT can identify regions of the heart with insufficient Thallium supply in heart muscles affected by insufficient blood supply.

MCG VRDA analysis detects the multidimensional dynamics of the electrical activity caused by differences in functions of Electrical Action Potential (EAP) of normal heart tissues and abnormal ones, with hypoxia. Interaction of functions of EAP of normal and affected regions is creating the repolarization dynamics that is different from the normal repolarization of the heart muscles activity. Mesuronís MCG VRDA can detect Repolarization problem even without hypoxia event per say. EAP of heart muscles experienced with insufficient blood supply during prolong time also has different function due to changes in chemistry of muscles activities adapting insufficient blood supply. As a result, the MCG can detect abnormalities even with no presence of hypoxia at the time of measurements. That is why MCG results in CSMC study were so similar to SPECT, even when taking the MCG data on patients at rest.

Conclusion: MCG VRDA is a rapid noninvasive, no radiation, no contact, no pharmaceuticals, no physical exercise test delivering results with indications of high risk and low risk cardiac patients (related to ventricle repolarization abnormalities) with high positive and negative predictive values."

     
 

 

Clinical Value of Mesuron's MagnetoCardioGraphy

 

#1 Emergency Medicine - ER, ED and Chest Pain Units

Mesuron's MCG is providing a rapid noninvasive, no radiation, no contact, no pharmaceuticals test delivering results that could be used to rule-out low risk cardiac patients with chest pain admission with very high negative predictive value. It also delivers rapid result for chest pain patients having high risk Ventricle Repolarization Abnormalities (MI or ischemic cardiac events), with high positive predictive values. It also gives an indication for the low risk cardiac patients for further evaluation and follow up.

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#2 Cardiology

Mesuron's MCG system such as "Avalon-H90" performs in regular cardiology office.

It will be capable of providing a millisecond by millisecond high spatial resolution of the electric activity map over the human heart within a minute, with the patient resting and no electrodes attached using only single measurement above the human chest

Due to its inherent synchronization over the whole magnetic map and using a single, completely contactless measurement of the electric map during 90 seconds this system will address a whole range of issues, including detection of the heart ventricle repolarization problems related to the ischemic heart disease (delivering results similar to the SPEC) as well as fast transitory, irregular processes, such as fast ventricular tachycardia.

Please visit our Bibliography web page to learn more about MCG

 

If you have any questions or would like to submit a request for quotation, please, click here Request Form


 

Multi-Channel custom SQUID Magnetometers

 

 Mesuron Inc.  also develops and manufactures custom SQUID Magnetometers for other applications. We created a stand-alone product line of the state-of-the-art low noise non-magnetic cryostats  for different SQUID Magnetometer configurations. Our products have the best quality and lowest prices in the field.

 

Full tensor magnetic flax SQUID Magnetometers (Geophysics or similar applications)

 

SQUID-magnetometers in Horizontal orientation

 

Multi-Channel custom SQUID Magnetometers for

Magnetic Bio-Markers Localization

 

 Mesuron Inc. is proposing uniquely designed SQUID magnetometers based on second order gradiometer sensors with a variety of relative sensor configurations and sensor designs. These are intended to reliably operate in open, non-magnetically shielded types of environment such as a regular hospital room. One of the promising directions of using this system is detection and localization of different cancer types in the human body in conjunctions with magnetic bio-markers for cancerous cells. The Mesuron team has extensive experience and was involved in development and production of commercial SQUID magnetometers for MCG use. For example, systems with 9 and 36 measuring SQUID sensors capable of localizing Magnetic Dipoles of small magnetic source activity (several femtotesla) with millimeter accuracy.
Presently  Mesuron Inc. is designing a relatively inexpensive, user-friendly SQUID magnetometer system with about 90 channels for MCG and Magnetic Bio-Markers localization.
It will be capable of providing a millisecond by millisecond, high spatial resolution multidimensional magnetic activity map over the human body. 
Due to the nature of the sensor configuration and its inherent synchronization over the whole magnetic map using a single completely contactless measurement, in one minute, the system creates the most comprehensive measurement data for inverse solution software for magnetic dipole localization. This is not only for precise single source localization but for multiple source localization as well!
 Mesuron Inc. is also proposing less expensive SQUID magnetometers for single magnetic source localization by utilizing several second order gradiometers in configurations that provide sufficient data for using the inverse solution software.

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If you have any questions or would like to submit a request for quotation, please, click here Request Form

     
 

 

About Mesuron Inc.

 

4A Northway Lane, Latham, NY, USA, 12110 Tel: 518-557-3510 email: Email: sales@mesuron.com

 

Incorporated in 2011,  Mesuron Inc. is a late development-stage company engaged in the design, development, manufacturing and marketing of non-invasive systems to measure and analyze bio-magnetic signals from the hearts of humans and animals.

The Companyís goal is to become the dominant purveyor of magnetometry systems for multiple biomedical applications. At present, the Company's focus is on the cardiac diagnostic applications.  Mesuron Inc. strategy has been developing and manufacturing of reliable, affordable systems optimally configured to solving clinical diagnostic problems, and to clinically validate its products.  

Founded by Alexander Bakharev, a cryogenic expert and successful entrepreneur,  Mesuron Inc. began the US operations in 2011.

Prior to  Mesuron Inc., Mr. Bakharev was the founder of the Russian Krionit Scientific Technical Enterprise. The company was involved in the development and manufacturing of different kinds of SQUID magnetometers, such as SQUID Microscopes, SQUID MagnetoEncephaloGraphs (MEG) and MagnetoCardioGraphs (MCG). Krionit had sold equipment to several US universities including Stony Brook University, US Naval Research Laboratory, IBM, LG Electronics, Samsung in Korea, customers in the UK, Germany and other companies around the globe.

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Clinical MagnetoCardioGraphy (MCG)

 Mesuron Inc. is a US commercial company specializing in the development and fabrication of  SQUID-based magnetometers for various applications including Clinical MagnetoCardioGraphy (MCG) systems

for heart scan procedures.  We have more than 30 years of extensive experience in developing SQUID Magnetometers include Clinical heart scan SQUID Magnetometers (MagnetoCardioGraphs)

which reliably operate in open, magnetically non-shielded types of environment, such as a regular hospital room. Our Clinical Heart Scan SQUID Magnetometers (MagnetoCardioGraphs)  

measure electromagnetic signals directly from the human heart without any contact with the patient's  body. Our company's unique magnetic noise reduction technology allows 

measuring the heart signal  in real hospital environment in close proximity to hospital freight elevators, working printers, computers and moving hospital personnel.

 Mesuron Inc.  also develops and manufactures custom SQUID Magnetometers for other applications. We created a stand-alone product line of the state-of-the-art low noise non-magnetic cryostats 

 for different SQUID Magnetometer configurations. Our products have the best quality and lowest prices in the field.

If you have any questions or would like to submit a request for quotation, please, click here Request Form 

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